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What are psychobiotics

The History of Psychobiotics

the history of psychobiotics

The History of Psychobiotics

~5000 BC: Fermentation

Humans have been fermenting food for thousands of years for preservation. Fermentation kills pathogens and promotes healthy bacteria growth on food, providing natural probiotic benefits to your gut-microbiome when you eat it. Because probiotics naturally reduce inflammation, and humans were eating fermented foods before refrigeration was invented, psychobiotics were a natural part of every diet.

Columbus & Syphilis

Some historians say that Columbus brought syphilis back to Europe from S. America in the late 1400s. The responsible bacteria, Treponema pallidum, became known as one of the first bacteria to influence mood and mental health when scientists discovered syphilis patients also developed depression, irritability, and memory problems.

1928: Penicillin

In 1928, Alexander Fleming discovers Penicillin, leading to the introduction of antibiotics. This was both a blessing and a curse – while antibiotics kill harmful and deadly bacteria in your body, they also eliminate the healthy, good bacteria in your gut.

In 2015 the Journal of Psychiatry published a study on the link between antibiotic use and mood disorders like depression & anxiety. Results showed that antibiotic exposure is associated with increased risk for depression and anxiety, compounding as dosage frequency goes up.

May 2000: Walkerton

E. Coli contaminates the city water supply in Walkerton, Ontario, causing thousands of residents to develop acute bacterial gastroenteritis. Hundreds develop long term IBS and depression as a result. Pre-existing depression doubled your chances of developing IBS.

2000-2008: Sad Mice

Canadian scientists transplant fecal matter from humans with IBS into germ free mice. The mice develop anxiety-like behavior, demonstrating there is a connection between the gut and the brain. This is one of the earliest indicators that behavior and mood are influenced by the gut-microbiome.

2017: Psychobiotic Revolution

Scott Anderson, Dr. John Cryan, and Dr. Ted Dinan publish The Psychobiotic Revolution, a revolutionary book based on their combined research on cutting edge science of the Gut-Brain Connection, helping give credibility to the theory that psychobiotics have real potential to help heal mood disorders.


Nutriotix was formed in 2019 to help raise awareness of psychobiotic benefits and to provide natural solutions for people suffering from mental health issues. Adding probiotics to your diet, through food or supplements, can help your body control inflammation which may help lower depression, ease anxiety, and can lead to a more positive overall mood. Nutriotix PsychoBiotic-10 combines a range of diverse bacterial strains with mood enhancing botanicals like Passionflower and Chamomile to promote healthier wellness and a happier mood and mind.


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